Pharmacogenetics – Per Click Health

Pharmacogenetic

Allows Clinicians To Better Understand How Their Patients Will Espond To Certain Medications.

Why Pgx Testing?

Pharmacogenetic (PGx) Testing is one of our greatest assets in preventing ADRs. These tests analyze genetic information to predict how someone will respond to specific medications. This leads to more personalized medication plans, less risk from “trial and error” prescriptions, and reduced costs for patients and providers.

Identify Which Drug May Be Most Effective Before Treatment Starts

PGx testing can help clinicians choose the most effective drug for each patient, minimize the risk of adverse reactions, and reduce hospitalizations.

Reduce The Risk Of Adverse Events Related To Certain Drugs

PGx testing can assess a patient’s risk for adverse drug reactions before they take the medication which can improve patient safety and minimize costs for healthcare facilities.

Adjust And Optimize The Dose Of Current Medications

PGx testing can help clinicians predict the appropriate dose of medication for their patient. This allows them to create more personalized medication plans to maximize efficacy and reduce pharmacy costs.

PGx testing can help clinicians choose the most effective drug for each patient, minimize the risk of adverse reactions, and reduce hospitalizations.

Improve Patient Care

PGx test results become part of a patient’s medical record, allowing physicians to make more informed decisions when prescribing medications for future medical issues.

What Pgx Can Tell Us?

PGx testing can reveal if a person is a fast, normal, or slow metabolizer. A person’s metabolism changes the way their body responds to medication, including:

Toxicity

Excessive amounts of the drug accumulate in the bloodstream, resulting in ADRs

Lack Of Efficacy

The bloodstream cannot absorb enough of the drug to achieve a therapeutic effect.

Hypersensitivity

Normal amounts of the drug enter the bloodstream, but even this is enough to trigger severe reactions in people with hypersensitivity to the medication.

PGx Focus Panel: Includes genes associated with drug metabolism with high-level evidence and clinically actionable guidelines.

PGx Comprehensive Panel: IIncludes genes associated with drug metabolism with high- level evidence and clinically actionable guidelines, in addition to genes with PharmGKB evidence of 2 or higher.

Adverse Drug Reaction Statistics* (ADR)

ADRs are a leading cause of morbidity and mortality in healthcare, causing approximately 100,000 deaths annually.

More than 2 million serious ADRs occur every year.

Nursing homes experience approximately 350,000 ADRs per year.

^* https://www.fda.gov/drugs/drug-interactionslabeling/preventable-adverse-drug-reactionsfocus-drug-interactions